منابع مشابه
Evolution: An exception that proves the rule
A careful comparative analysis suggests a simple explanation for a category of exceptions to the general correlation between separate sexes in plants -- dioecy -- and self-incompatibility. In some genera, polyploidy causes failure of self-incompatibility, and dioecy may then evolve.
متن کاملNeoadjuvant pertuzumab: the exception that proves the rule?
The original impetus for neoadjuvant therapy for breast cancer was to render patients with locally advanced breast cancer operable. In subsequent clinical trials, the key goals of neoadjuvant treatment were to improve surgical options for patients, and to determine whether earlier administration of systemic therapy would lower the risk of breast cancer recurrence. In the end, that latter object...
متن کاملPrimary age-related tauopathy and the amyloid cascade hypothesis: the exception that proves the rule?
Extensive data supports the amyloid cascade hypothesis, which states that Alzheimer's disease (AD) stems from neurotoxic forms of the amyloid-beta (Aβ) peptide. But the poor correlation between Aβ plaques and neurodegeneration/cognitive impairment, the spaciotemporal disparity between Aβ and tau pathology, and the disappointing results following several large clinical trials using Aβ-targeting ...
متن کاملHormone replacement therapy and endothelial function: the exception that proves the rule?
The endothelium plays a central role in the regulation of vascular homeostasis by releasing paracrine factors that influence vascular tone, thrombosis, and inflammation in the arterial wall.1 A principal endothelial product responsible for homeostasis is nitric oxide (NO), which is synthesized by the endothelial isoform of NO synthase2 in response to a number of stimuli, including increased she...
متن کاملThe Exception That Proves the Rule: An Interview with Jenny Graves
Close to 20 years ago, I was contacted by an Australian woman who was planning to map the locations of genes that are X-linked in humans in some odd Australian critters, the monotremes. These animals comprise a distantly related branch of mammals that have hair and lactate, but additionally lay eggs. She wanted a probe from our lab, and, in exchange, little vials of DNA from spiny echidna and p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Political Philosophy
سال: 2009
ISSN: 0963-8016
DOI: 10.1111/j.1467-9760.2009.00358.x